Botulinum toxin injection into vocal cord in the treatment of malignant coprolalia associated with Tourette's syndrome
Identifieur interne : 005692 ( Main/Exploration ); précédent : 005691; suivant : 005693Botulinum toxin injection into vocal cord in the treatment of malignant coprolalia associated with Tourette's syndrome
Auteurs : Burton L. Scott [États-Unis] ; Jankovic [États-Unis] ; Donald T. Donovan [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 1996-07.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Enfant.
English descriptors
- KwdEn :
- Adolescent, Attention deficit hyperacitivity disorder, Botulinum Toxins (administration & dosage), Botulinum toxin, Botulism, Case study, Chemotherapy, Child, Coprolalia, Humans, Injections, Intramuscular, Language disorder, Male, Obsessive compulsive disorder, Tic, Tics, Tourette Syndrome (drug therapy), Tourette Syndrome (genetics), Tourette's syndrome, Toxin, Treatment, Treatment Outcome, Treatment efficiency, Verbal Behavior (drug effects), Vocal Cords (drug effects), Vocal cord.
- MESH :
- chemical , administration & dosage : Botulinum Toxins.
- drug effects : Verbal Behavior, Vocal Cords.
- drug therapy : Tourette Syndrome.
- genetics : Tourette Syndrome.
- Adolescent, Humans, Injections, Intramuscular, Male, Treatment Outcome.
Abstract
We describe a 13‐year‐old boy with Tourette's syndrome (TS) manifested chiefly by severe coprolalia, obsessive compulsive disorder, and attention deficit hyperactivity disorder. He was treated with unilateral injections of botulinum toxin to the vocal cord and experienced marked improvement in coprolalia as well as marked reduction in the premonitory urges associated with the vocal tics and coprolalia. As a result of the improvement, the patient was able to attend school and church and was able to socialize. Botulinum toxin may interfere with a sensory reflex are required to perpetuate tics and coprolalia in TS, possibly by reducing local build‐up of tension or muscle contraction in affected areas.
Url:
DOI: 10.1002/mds.870110413
Affiliations:
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Le document en format XML
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<term>Botulinum toxin</term>
<term>Botulism</term>
<term>Case study</term>
<term>Chemotherapy</term>
<term>Child</term>
<term>Coprolalia</term>
<term>Humans</term>
<term>Injections, Intramuscular</term>
<term>Language disorder</term>
<term>Male</term>
<term>Obsessive compulsive disorder</term>
<term>Tic</term>
<term>Tics</term>
<term>Tourette Syndrome (drug therapy)</term>
<term>Tourette Syndrome (genetics)</term>
<term>Tourette's syndrome</term>
<term>Toxin</term>
<term>Treatment</term>
<term>Treatment Outcome</term>
<term>Treatment efficiency</term>
<term>Verbal Behavior (drug effects)</term>
<term>Vocal Cords (drug effects)</term>
<term>Vocal cord</term>
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<term>Vocal Cords</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Tourette Syndrome</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Tourette Syndrome</term>
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<term>Humans</term>
<term>Injections, Intramuscular</term>
<term>Male</term>
<term>Treatment Outcome</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Botulisme</term>
<term>Chimiothérapie</term>
<term>Coprolalie</term>
<term>Corde vocale</term>
<term>Efficacité traitement</term>
<term>Enfant</term>
<term>Etude cas</term>
<term>Tic</term>
<term>Toxine</term>
<term>Traitement</term>
<term>Trouble langage</term>
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<front><div type="abstract" xml:lang="en">We describe a 13‐year‐old boy with Tourette's syndrome (TS) manifested chiefly by severe coprolalia, obsessive compulsive disorder, and attention deficit hyperactivity disorder. He was treated with unilateral injections of botulinum toxin to the vocal cord and experienced marked improvement in coprolalia as well as marked reduction in the premonitory urges associated with the vocal tics and coprolalia. As a result of the improvement, the patient was able to attend school and church and was able to socialize. Botulinum toxin may interfere with a sensory reflex are required to perpetuate tics and coprolalia in TS, possibly by reducing local build‐up of tension or muscle contraction in affected areas.</div>
</front>
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<region><li>Texas</li>
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<tree><country name="États-Unis"><region name="Texas"><name sortKey="Scott, Burton L" sort="Scott, Burton L" uniqKey="Scott B" first="Burton L." last="Scott">Burton L. Scott</name>
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<name sortKey="Donovan, Donald T" sort="Donovan, Donald T" uniqKey="Donovan D" first="Donald T." last="Donovan">Donald T. Donovan</name>
<name sortKey="Jankovic" sort="Jankovic" uniqKey="Jankovic" last="Jankovic">Jankovic</name>
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